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BRILLIANT THALLIUM FLEX

Superior Thallium Flux Assay for High Throughput screening. Significant saving compared to FluxOR Potassium Ion Channel Assay
No Wash Thallium Assay


 

No Wash Thallium Assay

Price: $690.00

PRODUCT CODE: 11000-10


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Description Product Information References
 
ION Biosciences Brilliant Thallium Assay is a total assay solution for multi-well plate-based, high-throughput measurements of Tl+ flux through K+, Na+, non-selective cation channels, and some Na+ or K+ transporters. The ION Biosciences Brilliant Thallium Assay is also useful for a wide range of effectors of ion channels and transporters including G protein-coupled receptors, lipid and protein kinase, for example. In multi-well, plate-based formats, the Brilliant Thallium Assay can be used to discover and characterize the effects of tens to many tens-of-thousands of compounds and environmental factors on effectors of Tl+ flux. Over the past 15 years, fluorescence-based measures of Tl+ flux have been widely utilized to discovery small molecule modulators of a host of Ion channels, transporters, GPCRS and other targets of interest for both drug discovery and basic research. Inside the ION Brilliant Assay package, you will find all the reagents necessary for preparation of the Brilliant Thallium Assay for use as a washed or no wash assay for adherent and non-adherent cells. The addition of a probenecid solution and an extracellular background masking solution offers users the ultimate in compatibility for cells types which are difficult to load with fluorescent Tl+ indicators (e.g. Chinese Hamster Ovary, CHO cells) and when performing assays in complete, serum-containing cell culture medium is desired.
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